Resins for the Synthesis of Peptide Amide by Fmoc Chemistry

 

Rink Amide AM resin and Rink Amide MBHA resin are the most popular resins for the synthesis of peptide amide by Fmoc chemistry. Coupling of the first Fmoc amino acid to the resin can be achieved using the same protocol as for the solid phase peptide synthesis. Detachment of peptide amides from these supports can be effected in a single step by treatment with 95% TFA and appropriate scavengers.

 

13002

4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl-

phenoxy-acetamido-norleucylaminomethyl resin

Substitution: 0.4 - 0.8 mmole/g resin

Bead size 100- 200 mesh (polystyrene- 1% DVB)

1 g

5 g

25 g

$35

$150

$600

 

13003

4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl-

phenoxy-acetamido-norleucyl-MBHA resin

Substitution: 0.4 - 0.8 mmole/g resin

Bead size 100- 200 mesh (polystyrene- 1% DVB)

1 g

5 g

25 g

$35

$150

$600